Monday, January 26, 2009

Microbiology 201C Notes

Lecture 011509
Change takes work.
Microbiology is the study of microbes.
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Lecture 012009
Science is a test of knowledge. “Have you asked Mother Nature?”
Francis Bacon was a writer who developed a new way of teaching and research when it came to science.
Created Deductive reasoning.
Law – well established; law of gravity
Theory – general issues to describe an idea that has been supported over time by the use of tests using the idea;
Hypothesis – just an idea, may or may not be correct
Warburg – won a nobel prize(international prize) Nobel invented dynamite; Warburg go the nobel prize for chemistry, a jew who lived in berlin during the reign of hitler. “All of my hypotheses were wrong”
Science was the major discovery of the 17th century. Science is progressive, new information comes up all the time.
Microbiology – dealing with small living things, as a science different from other sciences
Bacteria
Natural history – study of things such as trees/animals
Touching is a great way to transmit diseases. Contagion – touching to distribute
Miasma – microbes working which causes smell
Resistance to disease – contracting the disease but building an immunity to it
Dyes – colouring a pigment to change the colour
Optics – lenses used to increase the size of something viewed
Organic chemistry – carbon based chemistry
Dyes, optics, and organic chemistry came from the germans
Golden age of microbiology – from 1857-1900, best time at 1875, during that time, the etiology of microbiology was established at that time. The beginning combination of brains and technology to further research microbiology.
Etiology – study of causes of diseases
Klch – german, country doctor and vetenarian, anthrax, argemedy and petri dish; page 18
Reach Chapter 1
1. Organism present – if a disease occurs then the organism will be present.
2. Isolated in pure culture – not contaminated by other cultures
3. Inject/infect a normal animal – causing a disease by artificially infecting an animal
4. Re-isolate agent from animal – relocate the disease after dead.
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Lecture 012209
For test Tuesday::
Lectures, Assigned readings
Chapter 1, read everything up to page 26. It will be on the quiz.
Chapter 9, pages 184-186,
Not on this test – Chapter 17 pg 370-end of chapter, Diseases.
Formula for biology:: P= (N * V)/ R;
P – probability (of getting some disease);
N – number of organism to which you are exposed.
V – virulence( capacity/ability) pathos pathogens(pathogens is a path crafted to begin) – damage to physical;
R – resistance; immune system; ability of the host to fight again
(Delta N)/Time
Binary fission – organism simulates (osmotrophs) nutrients by moving across the cell membrane. Once it has reached a large enough size it divides.
Generation Time – the time it takes bacteria to double.
Page 185 –
Lag phase – division is slow, bacteria is getting used to situation and nutrients
Log/Exponential phase – division is expansion where the increases is greater due to accustomization of nutrients and environments.
Stationary phase – division is steady however, death is moving at the same rate due to nutrient limiting
Death phase – no division, death increasing due to lack of nutrient or some other reaction that is killing them.
Begin writing reflective essay on Chapter 11. “Controlling/Limiting Growth”
Salt prevents microbial growth, MREs – meals ready to eat are deadly.
Sugar prevents microbial growth, prevents water from growth

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